Why does Vitamin D need Vitamin K2 to work properly?Updated 17 days ago

This is one of the most important reasons DAKE is formulated as a stack rather than isolated ingredients. Vitamin D significantly increases calcium absorption from the gut — which is exactly what you want for bone density and cellular function. But calcium that gets absorbed still needs to be directed to the right places: bones and teeth, not arteries and soft tissue. 

That's where Vitamin K2 comes in. K2 activates proteins — most notably osteocalcin and Matrix Gla Protein (MGP) — that shuttle calcium into bone and actively clear it from arterial walls. Without adequate K2, the calcium Vitamin D helps absorb has no reliable routing mechanism. Running high-dose D without K2 is a common oversight in supplementation. DAKE includes both K1 and K2 as MK-4 specifically so this pathway is covered.